
FOXO4-DRI 10mg
FOXO4-DRI is a synthetic senolytic peptide designed to selectively target and remove senescent cells—the so-called “zombie cells” that stop dividing but remain in tissues, releasing inflammatory factors that accelerate aging and disease.
- Product Introduction
Senolytic & Anti-Aging Peptide Research
What is FOXO4-DRI?
FOXO4-DRI is a synthetic senolytic peptide designed to selectively target and remove senescent cells-the so-called "zombie cells" that stop dividing but remain in tissues, releasing inflammatory factors that accelerate aging and disease.
By promoting the clearance of these dysfunctional cells, FOXO4-DRI anti-aging peptide is considered a breakthrough in regenerative medicine and longevity research. Its mechanism makes it highly valuable for studies in age-related decline, tissue repair, and organ health.
Sterile Workshop, Quality Assurance
We utilize sterile sealing and capping processes to minimize microbial contamination and prevent microbial interference with reactions, ensuring synthesis efficiency and product stability. We also utilize advanced instrumentation, including high-performance liquid chromatography (HPLC), gas chromatography (GC), and mass spectrometry (MS). From integrated production to quality control, we ensure high-quality products.
Benefits & Uses of FOXO4-DRI
Cellular Rejuvenation – Removes senescent cells, allowing healthier cells to thrive.
Anti-Aging Support – May reduce inflammation and oxidative stress associated with aging.
Improved Tissue Function – Promotes tissue regeneration and repair.
Cognitive Health – Potential neuroprotective benefits in age-related brain decline.
Enhanced Organ Function – Supports kidney, liver, and cardiovascular health.
Longevity Potential – Part of cutting-edge senolytic research in lifespan extension.
Molecular Structure
Type: Synthetic D-retro inverso peptide
Structure Basis: Modified FOXO4 sequence designed for enhanced stability and cell penetration.
Mechanism-Linked Design: Built to disrupt the interaction between FOXO4 and p53 proteins in senescent cells.
Mechanism of Action
FOXO4-DRI works by:
1.Targeting FOXO4-p53 Interaction – In senescent cells, FOXO4 binds to p53, preventing apoptosis (cell death). FOXO4-DRI blocks this interaction.
2.Inducing Senescent Cell Death – By releasing p53 from FOXO4, senescent cells undergo programmed cell death.
3.Reducing Inflammation – Eliminates cells that produce inflammatory cytokines (SASP).
4.Restoring Tissue Health – Creates space for new, healthy cells to replace dysfunctional ones.
FOXO4-DRI Compared with Similar Compounds
Dasatinib + Quercetin (D+Q) – Another senolytic combination, but less targeted than FOXO4-DRI.
Fisetin – Plant-derived senolytic with antioxidant benefits but less potent in cell-specific targeting.
Rapamycin – Works on mTOR inhibition for longevity, but does not directly clear senescent cells.
Key Difference: FOXO4-DRI is designed for precise senescent cell elimination, making it potentially more effective in cellular rejuvenation therapies.
Storage & Safety
Storage (Lyophilized Form): Store in a cool, dry place, away from direct light.
After Reconstitution: Refrigerate at 2–8°C; use within the recommended timeframe.
Handling: Maintain sterile conditions during reconstitution and administration
Side Effects
Research is still in early stages. Reported or possible side effects may include:
Temporary fatigue
Mild inflammation at injection site
Flu-like symptoms
Risk of excessive cell clearance if improperly dosed
Always consult a qualified healthcare professional before use.
FAQ
Our Advantage as a FOXO4-DRI peptide Supplier
High Purity: 99%+ verified peptide quality with COA.
GMP-Certified Manufacturing: Meets strict quality control standards.
Research-Grade: Suitable for advanced anti-aging and longevity studies.
Global Shipping: Safe, fast, and discreet delivery worldwide.
Expert Support: Guidance from experienced peptide specialists.
Order FOXO4-DRI 10mg Today
As a FOXO4-DRI anti-aging peptide, this compound represents one of the most promising senolytic research tools for aging, regeneration, and longevity.
Contact us today for COA verification, bulk pricing, and reliable global delivery. Partner with Guangzhou Yonsci Bio-Technology Co., Ltd.chem for trusted peptide supply.

Pls feel free to contact Vic for any questions:
Whatsapp:+852 9433 2308
Telegram: Your Telegram
Email: Jdy_gsyg@163.com
Our Advantages
End-to-End Peptide Production Capabilities
We provide a fully integrated manufacturing process-from solution preparation using stainless steel mixing tanks, sterile filtration via ultrafiltration systems, aseptic filling under laminar flow hoods, to lyophilization under strict temperature and pressure control. This ensures high purity, stability, and sterility of our peptide products, meeting stringent pharmaceutical and biotech industry standards.






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