
Cosmetics Peptides CAS 137665-91-9 Decapeptide-12 Raw Powder
Decapeptide-12 is a synthetic, bioengineered 10-amino-acid peptide widely used in cosmetic and dermatological formulations for skin brightening and pigmentation correction. It was originally developed by dermatologists to selectively inhibit tyrosinase, the key enzyme responsible for melanin production.
- Product Introduction
Cosmetics Peptides CAS 137665-91-9 Decapeptide-12 raw powder
Decapeptide-12 is a synthetic, bioengineered 10-amino-acid peptide widely used in cosmetic and dermatological formulations for skin brightening and pigmentation correction. It was originally developed by dermatologists to selectively inhibit tyrosinase, the key enzyme responsible for melanin production.
Compared with traditional whitening agents (hydroquinone, kojic acid, arbutin), Decapeptide-12 is more targeted, gentler, and suitable for long-term use, making it a premium ingredient in high-end brightening skincare.
Mechanism of Action
Decapeptide-12 acts as a potent tyrosinase inhibitor, suppressing melanin production within melanocytes.
This reduces the formation and transfer of pigment granules, leading to lighter and clearer skin over time.
Key Functions & Benefits of Decapeptide-12
Powerful Melanin Reduction
Directly inhibits tyrosinase, reducing melanin synthesis at the source.
Effective for improving hyperpigmentation, melasma, dark spots, and PIH.
Corrects Dark Spots & Hyperpigmentation
Effective for:
- Melasma
- PIH (Post-inflammatory hyperpigmentation)
- Acne marks
- Sun spots
- Age spots
Safe Alternative to Hydroquinone
Comparable brightening effect without the irritation or regulatory concerns associated with hydroquinone.
Improves Skin Tone Uniformity
Promotes a brighter, clearer, more even complexion.
Ideal for Advanced Brightening Formulas
Suitable for premium skincare lines targeting discoloration and skin tone refinement.
Formulation Guidance
- Reconstitute in water; add during the cooling phase (<40°C).
- Compatible with niacinamide, tranexamic acid, alpha arbutin, and glutathione.
- For maximum efficacy, combine with multi-pathway brightening ingredients.
Hot tags
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