Raw Materials Chemical Research Peptide Larazotide CAS 258818-34-7
Larazotide is an intestinal epithelial tight-junction regulator that acts locally on the intestinal mucosal barrier without systemic absorption or metabolism. By interacting with claudin proteins on intestinal epithelial cells, it helps regulate tight-junction permeability and reduce the passage of incompletely digested macromolecules, allergens, and toxins into the bloodstream, supporting the repair and protection of the intestinal barrier (“leaky gut”).
- Product Introduction
What is Larazotide CAS 258818-34-7?
|
Puduct Name |
Larazotide |
|
Appreance |
White Powder |
|
CAS |
258818-34-7 |
|
MF |
C32H55N9O10 |
|
MW |
725.83 |
Larazotide is an intestinal epithelial tight-junction regulator that acts locally on the intestinal mucosal barrier without systemic absorption or metabolism. By interacting with claudin proteins on intestinal epithelial cells, it helps regulate tight-junction permeability and reduce the passage of incompletely digested macromolecules, allergens, and toxins into the bloodstream, supporting the repair and protection of the intestinal barrier ("leaky gut").
Application&Function
Larazotide is primarily developed for the management of Celiac Disease and may help alleviate symptoms such as diarrhea, abdominal pain, and bloating after the ingestion of gluten-containing foods. Ongoing research is also exploring its potential as an adjunct therapy for inflammatory bowel diseases (including Crohn's disease and ulcerative colitis) and irritable bowel syndrome (IBS).
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