Dutasteride Raw Powder CAS 164656-23-9

Dutasteride is a potent dual 5α-reductase inhibitor used extensively in pharmaceutical and dermatological research. By inhibiting both Type I and Type II 5α-reductase enzymes, Dutasteride provides near-complete suppression of dihydrotestosterone (DHT)—the primary androgen responsible for androgenetic alopecia (AGA) and benign prostatic hyperplasia (BPH).

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Product Introduction

Dutasteride Raw Powder | Dual 5α-Reductase Inhibitor for Hair Loss & Prostate Research

Dutasteride is a potent dual 5α-reductase inhibitor used extensively in pharmaceutical and dermatological research. By inhibiting both Type I and Type II 5α-reductase enzymes, Dutasteride provides near-complete suppression of dihydrotestosterone (DHT)-the primary androgen responsible for androgenetic alopecia (AGA) and benign prostatic hyperplasia (BPH).

Compared with first-generation inhibitors, Dutasteride offers stronger efficacy, broader enzyme coverage, and longer biological activity, making it a preferred choice for advanced hair loss and prostate health research.

Product Name	Dutasteride
CAS Number	164656-23-9
Molecular Formula	C₂₇H₃₀F₆N₂O₂
Molecular Weight	528.53
Appearance	White to off-white crystalline powder
Chemical Class	4-azasteroid
Solubility	Soluble in organic solvents
Stability	Stable under standard storage conditions

What Is Dutasteride?

Dutasteride is a synthetic steroidal compound that blocks the enzymatic conversion of testosterone into DHT by inhibiting:

Type I 5α-reductase (skin, scalp, sebaceous glands)
Type II 5α-reductase (prostate, hair follicles)

This dual inhibition results in up to 90–95% reduction in systemic and scalp DHT levels, offering significantly stronger androgen suppression than selective inhibitors.

Dutasteride Mechanism of Action

01/

Dual Enzyme Inhibition

Dutasteride suppresses both major isoforms of 5α-reductase, preventing DHT synthesis at multiple tissue sites.

02/

DHT Reduction

Lower DHT levels lead to:

Reduced androgen-driven hair follicle miniaturization
Decreased prostate volume in BPH research

03/

Long-Term Activity

Due to its long half-life, Dutasteride maintains stable DHT suppression with sustained biological effects.

Dutasteride Benefits

Powerful suppression of DHT production
Superior efficacy compared to Finasteride
Slows or halts progression of androgenetic alopecia
Preserves hair follicle structure and function
Reduces prostate enlargement in BPH research
Suitable for oral and topical formulation studies

FAQ

Q1: Is Dutasteride stronger than Finasteride?
Yes. Dutasteride inhibits both Type I and II 5α-reductase, resulting in much greater DHT suppression.

Q2: Can Dutasteride be used in topical research?
Yes. Low-dose topical formulations are actively researched to reduce systemic exposure.

Q3: Does Dutasteride affect testosterone levels?
It mainly reduces DHT and does not significantly lower total testosterone.

Q4: Can it be combined with Minoxidil?
Yes. Combination research often shows synergistic hair preservation effects.

Why Choose Our Dutasteride?

✅High-purity raw material (≥98%)
✅Full analytical documentation (COA, HPLC)
✅Stable bulk supply (mg to kg scale)
✅ Direct manufacturer pricing from China

✅ Support for hair-loss R&D and formulation projects
✅Reliable global shipping and compliance support