What Are Some Anti-aging Peptides?

Anti-aging peptides primarily work by promoting collagen synthesis, inhibiting expression lines, or repairing the skin barrier. Common anti-aging active peptides include acetyl hexapeptide-8, palmitoyl tripeptide-1, copper peptide (tripeptide-1 copper), and dipeptide diaminobutyryl benzylamide diacetate (a snake venom peptide). Their mechanisms of action and intended use vary, so the correct choice should be based on skin condition and needs.

Acetyl hexapeptide-8 (also known as "hexapeptide") is one of the most widely used anti-wrinkle peptides. It primarily works by inhibiting neurotransmitter release and reducing muscle contraction, thereby reducing dynamic wrinkles (such as crow's feet and forehead wrinkles). Its effects are similar to botulinum toxin, but gentler and suitable for daily skincare. Palmitoyl tripeptide-1 stimulates fibroblasts to produce collagen and hyaluronic acid, improving skin elasticity and firmness, and has some effect on static wrinkles (such as nasolabial folds). Copper peptide combines repair and anti-aging properties, promoting wound healing while reducing free radical damage, making it suitable for sensitive skin or skin with a compromised barrier. If your skin is experiencing sagging or dullness, consider a combination product. For example, the combination of Pentapeptide-3 and Tetrapeptide-7 can synergistically inhibit inflammatory factors and delay photoaging. Palmitoyl Tetrapeptide-7 combined with Palmitoyl Pentapeptide-4 can enhance skin's support. However, it's important to note that the molecular weight, concentration, and formula stability of the peptide ingredient directly impact its effectiveness, so it's recommended to choose a clinically proven brand.