
Biotin-Ghk Biotinoyl Tripeptide-1 CAS 299157-54-3 Hair Growth
Biotinoyl Tripeptide-1 is a highly effective bioactive peptide conjugate combining the well-known benefits of biotin (vitamin B7) with a short tripeptide chain optimized for hair follicle stimulation and scalp vitality. Recognized in cosmetic science as a multifunctional ingredient, Biotinoyl Tripeptide-1 supports hair growth, reduces shedding, and strengthens weakened hair by targeting follicular signaling at a cellular level.
- Product Introduction
Biotinoyl Tripeptide-1 (CAS 299157-54-3) Premium Hair & Scalp Peptide for Hair Growth and Follicle Strength
Biotinoyl Tripeptide-1 is a highly effective bioactive peptide conjugate combining the well-known benefits of biotin (vitamin B7) with a short tripeptide chain optimized for hair follicle stimulation and scalp vitality. Recognized in cosmetic science as a multifunctional ingredient, Biotinoyl Tripeptide-1 supports hair growth, reduces shedding, and strengthens weakened hair by targeting follicular signaling at a cellular level.
It is widely utilized in advanced hair care formulations - including serums, tonics, ampoules, and professional dermatology products - and is compatible with both cosmetic and cosmeceutical applications.
What Is Biotinoyl Tripeptide-1?
Biotinoyl Tripeptide-1 is a synthetic peptide combining the hair-supportive vitamin biotin with a short peptide sequence designed to promote receptor-mediated follicular signaling. The biotin moiety enhances penetration and activity in hair follicle environments, while the peptide component interacts with key cellular processes that support:
- Hair anchoring and strength
- Follicle activity and longevity
- Scalp microenvironment stability
- Reduced hair shedding

Biotinoyl Tripeptide-1 Mechanism of Action
Follicular Receptor Activation
Biotinoyl Tripeptide-1 binds to specific receptors in hair follicles, triggering cellular pathways that:
- Strengthen the follicle matrix
- Support dermal papilla activity
- Promote keratinocyte and follicular cell function
Biotin Delivery Enhancement
Biotin is essential for:
- Keratin synthesis
- Fatty acid metabolism
- Scalp health maintenance
By combining it with a tripeptide, this molecule offers improved delivery to active sites.
Hair Growth Signaling
Biotinoyl Tripeptide-1 helps modulate growth-related protein expression, enhancing:
- Cell renewal
- Hair cycling stability
- Resistance to miniaturization
Biotinoyl Tripeptide-1 Benefits
Hair Strength & Integrity
Strengthens weakened hair fibers
Enhances tensile resilience of hair strands
Hair Growth Support
Encourages thicker, fuller hair appearance
Supports active hair-producing follicles
Reduced Shedding
Helps maintain hair count
Improves follicle anchoring
Scalp & Follicle Health
Supports scalp condition
Enhances microenvironment for hair growth
Formulation Advantages
Water-soluble and easy to blend
Compatible with serums, lotions, gels, and scalp treatments
Comparison With Related Hair Peptides
|
Peptide |
Primary Action |
Best Use |
|
Biotinoyl Tripeptide-1 |
Follicle receptor sensitization & biotin delivery |
Hair growth & strength |
|
Copper Peptides (GHK-Cu) |
Tissue repair & inflammation modulation |
Hair & skin regeneration |
|
Kisspeptin-10 |
Hormonal axis support |
Endocrine-linked hair studies |
|
RU58841 |
Androgen receptor antagonism |
DHT-related hair loss |
|
SM04554 |
Wnt pathway activation |
Follicle regeneration |
FAQ
Q: Is this peptide suitable for sensitive scalps?
A: Yes - due to its non-hormonal mechanism, it is widely formulated for sensitive scalp products.
Q: Can it be combined with other actives?
A: Yes - compatible with minoxidil, peptides, vitamins, and botanical extracts.
Q: Does it act systemically?
A: It is designed for topical action in hair care formulations.
Q: What effects can users expect?
A: Improved hair thickness, reduced shedding, stronger hair strands, and healthier follicles (based on formulation and use).
Product Claims
Hair follicles fortified for resilience
Less shedding, stronger root attachment
Supports fuller, thicker hair appearance
Perfect for serum and scalp treatment formulations
Safety & Disclaimer
This product is intended for cosmetic and research use only. Not approved for human or veterinary therapeutic use. Compliance with local laws and regulatory requirements is the responsibility of the purchaser.
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More Anti-Hair loss products:
|
Seripiprant |
CB-03-01 |
Seripiprant |
|
WAY 316606 |
RU58841 |
Finasteride |
|
KX-826 |
SM04554 |
Dutasteride |
|
Minoxidil |
Ghk-cu |
Biotinoyl Tripeptide-1 |

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